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π†πŒ΄πŒΉπŒ»πŒ°:Cyclotide biosynthesis.png

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πŒΌπŒ°πŒΏπ‚πŒ²πŒΏπƒ πƒπŒΊπŒ΄πŒΉπ‚πŒ΄πŒΉπŒ½πƒ

πƒπŒΊπŒ΄πŒΉπ‚πŒ΄πŒΉπŒ½πƒ
English: The cyclotide precursor is comprised a hydrophobic signal peptide that targets the precursor to the Endoplasmic Reticulum (ER), an N-terminal propeptide that then targets it to the vacuole, a cyclotide domain and a final C-terminal propeptide necessary for cyclisation. The cyclotide domain folds in the ER, after which it is trafficked to the vacuole and the cyclotide domain is cyclised by an asperginyl endopeptidase. (PDB: 1WN8, 1NB1​)
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πŒ±π‰πŒΊπŒ°π‚πŒ΄πŒΉπƒ Evolution and evolvability

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πŒ°π„π„πŒ΄πŒΊ 𐌳𐌰𐌲/𐌼𐌴𐌻 𐌳𐌿 πŒ±πŒ°πŒ½πŒ³π…πŒΎπŒ°πŒ½ π†πŒ°πŒΎπŒ» πƒπ…πŒ°πƒπ…πŒ΄ πŒ²πŒ°πŒ±πŒ°πŒΉπ‚πŒ·π„πŒΉπŒ³πŒ° 𐌹𐌽 𐌸𐌰𐌼𐌼𐌰 𐌼𐌴𐌻𐌰.

πŒΌπŒ΄πŒ»πŒ»πŒ΄πŒΉπ„πŒΉπŒ»πŒ° π†π‚πŒΉπƒπŒ°πŒ·π„πƒπ…πŒ°πŒ·πƒπ„πŒΏπƒπŒ±π‚πŒΏπŒΊπŒΎπŒ°πŒ½πŒ³πƒ/πŒ±π‚πŒΏπŒΊπŒΎπŒ°πŒ½πŒ³πŒΉπ…πŒ°πŒΏπ‚πŒ³
𐌽𐌿05:24, 13 πŒΎπŒΏπŒ½πŒΉπŒΏπƒ 2016πŒ»πŒ΄πŒΉπ„πŒΉπŒ»πŒ°π†π‚πŒΉπƒπŒ°πŒ·π„πƒ πŒΏπƒπŒΌπŒ΄π‚πŒΎπŒ° 𐌹𐌽 05:24, 13 πŒΎπŒΏπŒ½πŒΉπŒΏπƒ 20161,021 Γ— 695 (132 KB)Evolution and evolvabilityopaque background
05:15, 13 πŒΎπŒΏπŒ½πŒΉπŒΏπƒ 2016πŒ»πŒ΄πŒΉπ„πŒΉπŒ»πŒ°π†π‚πŒΉπƒπŒ°πŒ·π„πƒ πŒΏπƒπŒΌπŒ΄π‚πŒΎπŒ° 𐌹𐌽 05:15, 13 πŒΎπŒΏπŒ½πŒΉπŒΏπƒ 20161,003 Γ— 720 (145 KB)Evolution and evolvabilityCross-wiki upload from en.wikipedia.org

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