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π†πŒ΄πŒΉπŒ»πŒ°:Epistasis and landscapes.png

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πƒπŒΊπŒ΄πŒΉπ‚πŒ΄πŒΉπŒ½πƒ
English: The top row indicates interactions between two genes that are either additive (a), show positive epistasis (b) or reciprocal sign epistasis (c). Below are fitness landscapes which display greater and greater levels of global epistasis between large numbers of genes. Purely additive interactions lead to a single smooth peak (d), as increasing numbers of genes exhibit epistasis, the landscape becomes more rugged (e) and when all genes interact epistatically the landscape becomes so rugged that mutations have seemingly random effects (f).
Date
πŒ±π‚πŒΏπŒ½πŒ½πŒ° Thomas, Shafee, (2014). "Evolvability of a viral protease: experimental evolution of catalysis, robustness and specificity". PhD Thesis. University of Cambridge.
πŒ±π‰πŒΊπŒ°π‚πŒ΄πŒΉπƒ Thomas Shafee

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20 πŒΎπŒΉπŒΏπŒ»πŒ΄πŒΉπƒ 2013

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𐌽𐌿10:41, 20 πŒΎπŒΉπŒΏπŒ»πŒ΄πŒΉπƒ 2013πŒ»πŒ΄πŒΉπ„πŒΉπŒ»πŒ°π†π‚πŒΉπƒπŒ°πŒ·π„πƒ πŒΏπƒπŒΌπŒ΄π‚πŒΎπŒ° 𐌹𐌽 10:41, 20 πŒΎπŒΉπŒΏπŒ»πŒ΄πŒΉπƒ 2013967 Γ— 788 (326 KB)Evolution and evolvabilityUser created page with UploadWizard

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